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Other names
5-Aminoisoleucine
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C6H14N2O2 | |
Molar mass | 146.190 g·mol−1 |
Appearance | White solid |
Density | 1.121 g/cm3 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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3-Methylornithine is an amino acid with the formula H2N(CH2)2CH(CH3)CH(NH2)CO2H. This amino acid contains two stereogenic centers, but only one stereoisomer (namely (3R)-3-methyl-D-ornithine) occurs in nature. It is produced from lysine by the action of the enzyme methylornithine synthase. The combination of lysine and 3-methylornithine, also mediated enzymatically, produces pyrrolysine, which, for some organisms, is a 22nd genetically coded amino acid.[1][2]
See also
References
- ^ Gaston, Marsha A.; Jiang, Ruisheng; Krzycki, Joseph A. "Functional Context, Biosynthesis, and Genetic Encoding of Pyrrolysine" Current Opinion in Microbiology 2011, vol. 14, pp. 342-349. doi:10.1016/j.mib.2011.04.001
- ^ Quitterer, F.; Beck, P.; Bacher, A.; Groll, M., "Structure and Reaction Mechanism of Pyrrolysine Synthase (PylD)", Angew. Chem. Int. Ed. 2013, volume 52, pp. 7033-7037. doi:10.1002/anie.201301164