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4-Methylhistamine
Names

Preferred IUPAC name 2-(5-Methyl-1H-imidazol-4-yl)ethan-1-amine
Identifiers
CAS Number	36507-31-0^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL275443^Y
ChemSpider	34368^Y
ECHA InfoCard	100.163.601
IUPHAR/BPS	1269
KEGG	C17929^Y
MeSH	4-methylhistamine
PubChem CID	37463
UNII	54ST71P9EE^Y
CompTox Dashboard (EPA)	DTXSID90957812
InChI InChI=1S/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9)^Y Key: UGYXPZQILZRKJJ-UHFFFAOYSA-N^Y InChI=1/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9) Key: UGYXPZQILZRKJJ-UHFFFAOYAJ
SMILES CC1=C(N=CN1)CCN
Properties
Chemical formula	C₆H₁₁N₃
Molar mass	125.17164 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

4-Methylhistamine is a histamine agonist selective for the H₄ subtype.^[1]

References

Agonists

Antagonists

Agonists	Amthamine Betazole Dimaprit Histamine HTMT Impromidine L-Histidine UR-AK49
Antagonists	Bisfentidine Burimamide Cimetidine Dalcotidine Donetidine Ebrotidine Etintidine Famotidine Isolamtidine Lafutidine Lamtidine Lavoltidine (loxtidine) Lupitidine Metiamide Mifentidine Niperotidine Nizatidine Osutidine Oxmetidine Pibutidine Quisultazine (quisultidine) Ramixotidine Ranitidine Roxatidine Sufotidine Tiotidine Tuvatidine Venritidine Xaltidine Zolantidine

Agonists	α-Methylhistamine Cipralisant Histamine Imetit Immepip Immethridine L-Histidine Methimepip Proxyfan
Antagonists	A-349821 A-423579 ABT-239 ABT-652 AZD5213 Bavisant Betahistine Burimamide Ciproxifan Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681

Agonists	4-Methylhistamine α-Methylhistamine Histamine L-Histidine OUP-16 VUF-8430
Antagonists	JNJ-7777120 Mianserin Seliforant Thioperamide Toreforant VUF-6002

See also: Receptor/signaling modulators; Monoamine metabolism modulators; Monoamine reuptake inhibitors

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