Names | |
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Preferred IUPAC name
(3S,6S,9S,15aR)-9-[(2S)-Butan-2-yl]-6-[(1-methoxy-1H-indol-3-yl)methyl]-3-(6-oxooctyl)octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.163.614 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C34H49N5O6 | |
Molar mass | 623.795 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Apicidin is a fungal metabolite, as well as a histone deacetylase inhibitor.[1]
References
- ^ Han, J. W.; Ahn, S. H.; Park, S. H.; Wang, S. Y.; Bae, G. U.; Seo, D. W.; Kwon, H. K.; Hong, S.; Lee, H. Y.; Lee, Y. W.; Lee, H. W. (November 2000). "Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin". Cancer Res. 60 (21): 6068–74. PMID 11085529.