Azel Roe (February 20, 1738 – December 2, 1815) was an American clergyman.

Roe was born in Setauket, Long Island. He was the son of John Roe.

He graduated from the College of New Jersey (now known as Princeton University) with a bachelor of arts degree in 1756 and received a doctorate in divinity from Yale in 1800.^{[1]: 17 and 85}

He received a license to preach from the New York Presbytery in 1759 or 1760 and was later ordained by the New York Presbytery. He was called as minister of the First Presbyterian Church in Woodbridge, NJ in 1763 and served there until his death.^[2][3]

He was a trustee of the College of New Jersey from 1778-1807.^[1]: 85

He served as moderator of the General Assembly of the Presbyterian Church in the United States of America at the 14th General Assembly in 1802.^[4]

He died on December 2, 1815.