Body-on-frame is a traditional motor vehicle construction method whereby a separate body or coach is mounted on a strong and relatively rigid vehicle frame or chassis that carries the powertrain (the engine and drivetrain) and to which the wheels and their suspension, brakes, and steering are mounted. Whereas this was the original method of building automobiles, body-on-frame construction is now used mainly for pickup trucks, large SUVs, and heavy trucks.

In the late 19th century, the frames, like those of the carriages they replaced, might be made of wood (commonly ash), reinforced by steel flitch plates, but in the early 20th century, steel ladder frames or chassis rapidly became standard. Mass production of all-metal bodies began with the Budd Company and the Dodge Brothers. All-metal bodies became common in the 1920s, except for Europe, which followed almost a decade later. Europe's custom-made or "coachbuilt" cars usually contained some wood framing or used aluminium alloy castings. Towards the beginning of international automobile assembly and construction, most manufacturers created rolling chassis consisting of a powertrain, suspension, steering column and a fuel tank that was then sent to a coachbuilder that added the body, interior and upholstery to the customers specific requests.

In contrast, unibody or monocoque designs, where panels within the body supported the car on its suspension, were developed by European manufacturers in the late 1920s with Budd USA (which had a number of large factories in Europe) and its technical knowhow. Because of the high cost of designing and developing these structures and the high cost of specialised machinery to make the large pressings required by this style of construction it is not used by low-volume manufacturers, who might construct an equivalent by welding steel tube to form a suitable space frame.

The Ford Model T carried the tradition of body-on-frame over from horse-drawn buggies, helping to facilitate high volume manufacturing on a moving assembly line.^[2] The use of steel ladder and X frame chassis allowed numerous vehicles to share a chassis and drivetrain while making changes to bodywork and interiors relatively easy, thus keeping costs down and minimizing design time. Over time the technology for unibody construction became economically feasible, assisted in recent decades by computer-aided design.^[3] in addition, modern creature comforts, luxury and power-assisted features, and extensive safety reinforcement of vehicles have all added substantial weight, the ability to offset this with unibody construction has proven advantageous.

A handful of small passenger vehicles switched to unibody construction by the end of the 1930s. The trend had started with cars like the Citroën Traction Avant (1934) and Opel Olympia (a General Motors design) introduced in 1935, and the short-lived, aborted Chrysler Airflow. Trucks, bus manufacturers, and large low-volume cars or those made in the United States continued to use separate bodies on "conventional" frames. Body-on-frame remains the preferred construction method for heavy-duty commercial vehicles (especially those intended to carry or pull heavy loads, such as trucks and some sport utility vehicles (SUVs)) but as production volumes rise, increasing numbers of SUVs and crossover SUVs are switching to unibody frames. Mass-market manufacturers Ford, General Motors, and Chrysler are abandoning true body-on-frame SUVs, opting, when sales volume permits, for more efficient unibody construction.^[4] Toyota currently manufactures the most body-on-frame SUVs with the 4Runner, Sequoia, Land Cruiser, Lexus GX, and Lexus LX, followed by Nissan with the Patrol, Armada, and Infiniti QX56/80.^[5]

The following is a list of SUVs and light-duty pickup trucks that have a body-on-frame construction.^{[as of?]} The list is divided by vehicle category.

• Suzuki Jimny

• Toyota 4Runner
• INEOS Grenadier
• Toyota Fortuner
• Toyota Land Cruiser Prado
• Lexus GX
• Mitsubishi Pajero Sport
• Nissan Terra
• SsangYong Rexton
• Isuzu MU-X
• Jeep Wrangler
• Ford Bronco
• Ford Everest
• Ford Explorer (until 2010)
• Kia Mohave
• Mercedes-Benz G-Class
• Mercury Mountaineer
• Lincoln Aviator (until 2005)
• Chevrolet TrailBlazer (until 2009)
• LDV D90
• TANK 300
• TANK 500

• Toyota Land Cruiser
• Toyota Sequoia
• Lexus LX
• Cadillac Escalade (ESV)
• Chevrolet Suburban
• Chevrolet Tahoe
• Hongqi LS7
• Nissan Patrol
• Nissan Armada
• GMC Hummer EV
• GMC Yukon (XL)
• Jeep Wagoneer (Grand Wagoneer)
• Ford Expedition (EL/Max)
• Lincoln Navigator (L)
• Yangwang U8
• Infiniti QX80

• Mitsubishi Zinger

• Toyota Innova (until 2021)
• Isuzu Panther

• Holden Colorado
• Ford Ranger
• GMC Canyon
• Isuzu D-Max
• Renault Alaskan
• SsangYong Musso
• Toyota Hilux
• Toyota Kijang
• Toyota Tacoma
• Mazda BT-50
• Mitsubishi Triton
• Nissan Frontier
• Nissan Navara
• Jeep Gladiator
• Volkswagen Amarok
• LDV T60
• GWM Ute Cannon

• Chevrolet Silverado
• Ford F-Series
• GMC Hummer EV
• GMC Sierra
• Nissan Titan
• Ram pickup
• Toyota Tundra

• Backbone chassis
• C-channel
• Coachwork
• Exoskeleton car
• Monocoque
• Skateboard (automotive platform)
• Semi-monocoque
• Space frame
• Subframe
• Superleggera

• Ford assembly line featuring body-on-frame car (historic)