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cytochrome P450, family 11, subfamily a, polypeptide 2

Identifiers

Organism

Symbol

CYP11A2

Other data

25: 22.3 - 22.31 Mb

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Structures	Swiss-model
Domains	InterPro

The Cyp11a2 is a fish gene encoding a CYP450 monooxygenase,^[1] which was originally identified in Zebrafish (Danio rerio),^[2] is the isozyme and paralogous of fish CYP11A1, catalyzes conversion of cholesterol to pregnenolone.^[3]

References

^ Uno T, Ishizuka M, Itakura T (July 2012). "Cytochrome P450 (CYP) in fish". Environmental Toxicology and Pharmacology. 34 (1): 1–13. Bibcode:2012EnvTP..34....1U. doi:10.1016/j.etap.2012.02.004. PMID 22418068.
^ Parajes S, Griffin A, Taylor AE, Rose IT, Miguel-Escalada I, Hadzhiev Y, et al. (August 2013). "Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme cyp11a2". Endocrinology. 154 (8): 2702–11. doi:10.1210/en.2013-1145. PMID 23671259.
^ Li N, Oakes JA, Storbeck KH, Cunliffe VT, Krone NP (February 2020). "The P450 side-chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish". The Journal of Endocrinology. 244 (2): 309–321. doi:10.1530/JOE-19-0384. PMID 31693487.

v t e Cytochromes, oxygenases: cytochrome P450 (Most belong to EC 1.14)
CYP1	A1 A2 A5 B1
CYP2	A6 A7 A13 B6 C8 C9 C18 C19 D6 E1 F1 J2 R1 S1 U1 W1
CYP3 (CYP3A)	A4 A5 A7 A37 A43
CYP4	A11 A22 B1 F2 F3 F8 F11 F12 F22 V2 X1 Z1
CYP5-20	CYP5 (A1) CYP6 (G1, M2) CYP7 (A1, B1) CYP8 (A1, B1) CYP9 CYP10 CYP11 (A1, A2, B1, B2, B3, C1) CYP12 CYP13 CYP14 CYP15 CYP16 CYP17 (A1) CYP18 CYP19 (A1) CYP20 (A1)
CYP21-49	CYP21 (A2) CYP22 (A1) CYP23 CYP24 (A1) CYP25 CYP26 (A1, B1, C1) CYP27 (A1, B1, C1) CYP28 (A1) CYP29 CYP35 (B1) CYP39 (A1) CYP46 (A1)
CYP51-69	CYP51 (A1, F1) CYP52 CYP53 A1 CYP55 A1 CYP56 A1 CYP61
CYP71-99	CYP71 (C1, C2, C3, C4, Z6, AJ4, AV1, BA1) CYP72A1 CYP73A1 CYP74 (D1) CYP75 (A1, B1) CYP76 (B6, M7) CYP79 (A1, A2, B1, B2, B3, D1, D2, D3, D4) CYP80 (A1, B1, G2) CYP81 (E1, E3, E7, E9) CYP88D6 CYP90C1 CYP93E1 CYP97C1 CYP99A3
CYP101-281	CYP101A1 CYP102A1 CYP105 A1 D7 CYP106A2 CYP107 A1 G1 CYP109 B1 E1 CYP111 CYP113A1 CYP119A1 CYP123 CYP125A1 CYP139 CYP147 CYP152 A1 B1 CYP154C3 CYP158A CYP161C CYP170 A1 B1 CYP176A1 CYP183A CYP197 CYP199A2 CYP255A
CYP301-499	CYP303A1 CYP305 M2 Halloween genes ( CYP302A1, CYP306A1, CYP307A1, CYP307A2, CYP314A1, CYP315A1) CYP318A1
CYP501-699	CYP503 CYP504B1
CYP701-999	CYP704B22 CYP710 CYP720A1

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