Charcot–Bouchard aneurysm

Technopedia Center

Faculty of Engineering and Computer Science
S1 Informatics S1 Information Systems S1 Information Technology S1 Computer Engineering S1 Electrical Engineering S1 Civil Engineering

faculty of Economics and Business
S1 Management S1 Accountancy

Faculty of Letters and Educational Sciences
S1 English literature S1 English language education S1 Mathematics education S1 Sports Education

Charcot–Bouchard aneurysm - Wikipedia

From Wikipedia, the free encyclopedia

Charcot–Bouchard aneurysm
Other names	Miliary aneurysms, Microaneurysms
Specialty	Cardiology
Diagnostic method	CT or MRI brain scan

Charcot–Bouchard aneurysms are aneurysms of the brain vasculature which occur in small blood vessels (less than 300 micrometre diameter). Charcot–Bouchard aneurysms are most often located in the lenticulostriate vessels of the basal ganglia and are associated with chronic hypertension.^[1] Charcot–Bouchard aneurysms are a common cause of cerebral hemorrhage. Charcot–Bouchard aneurysm rupture might be linked to senile plaque formation in the Alzheimer's disease.^[2]

Retinal microaneurysms are seen in conditions like diabetic retinopathy,^[3]^: 498 HIV related retinal microangiopathy,^[3]^: 467 sickle cell retinopathy,^[3]^: 533 idiopathic macular telangiectasia^[3]^: 601 etc. In diabetic retinopathy, due to breakdown in blood–retinal barrier, microaneurysms may leak plasma constituents into the retina, or it may thrombose.^[3]^: 498

Signs and symptoms

If a Charcot–Bouchard aneurysm ruptures, it will lead to an intracerebral hemorrhage, which can cause hemorrhagic stroke, typically experienced as a sudden focal paralysis or loss of sensation.^[1]

Pathophysiology

Charcot–Bouchard aneurysms are aneurysms in the small penetrating blood vessels of the brain. They are associated with hypertension. The common artery involved is the lenticulostriate branch of the middle cerebral artery. Common locations of hypertensive hemorrhages include the putamen, caudate, thalamus, pons, and cerebellum. ^{[citation needed]}

As with any aneurysm, once formed they have a tendency to expand and eventually rupture, in keeping with the Law of Laplace.^[4]^[5]

Diagnosis

Usually not detected by CT angiography.^[5] Retinal microaneurysms can be diagnosed using ophthalmoscopy, fundus photography, FFA, and OCT.^[6]

History

Charcot–Bouchard aneurysms are named for the French physicians Jean-Martin Charcot and Charles-Joseph Bouchard.^[7]^[8] Bouchard discovered these aneurysms during his doctoral research under Charcot.^[9]

References

^ ^a ^b Fausto, [ed. by] Vinay Kumar; Abul K. Abbas; Nelson (2005). Robbins and Cotran Pathologic Basis of Disease (7th ed.). Philadelphia: Elsevier/Saunders. ISBN 978-0-7216-0187-8.{{cite book}}: CS1 maint: multiple names: authors list (link)
^ Fu, Hualin; Li, Jilong; Du, Peng; Jin, Weilin; Gao, Guo; Cui, Daxiang (April 2023). "Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture". FEBS Letters. 597 (7): 1007–1040. doi:10.1002/1873-3468.14549. ISSN 0014-5793. PMID 36448495. S2CID 254095098.
^ ^a ^b ^c ^d ^e Salmon, John F. (2020). Kanski's clinical ophthalmology: a systematic approach (9th ed.). [Edinburgh]. ISBN 978-0-7020-7713-5. OCLC 1131846767.{{cite book}}: CS1 maint: location missing publisher (link)
^ E. Goljan, Pathology, 2nd ed. Mosby Elsevier, Rapid Review Series.
^ ^a ^b Nussbaum ES, Erickson DL. The fate of intracranial microaneurysms treated with bipolar electrocoagulation and parent vessel reinforcement. Neurosurgery. doi:10.1097/00006123-199911000-00031 . PMID 105499341999;45(5):1172-4; discussion 1174-5.
^ Dubow, Michael; Pinhas, Alexander; Shah, Nishit; Cooper, Robert F.; Gan, Alexander; Gentile, Ronald C.; Hendrix, Vernon; Sulai, Yusufu N.; Carroll, Joseph; Chui, Toco Y. P.; Walsh, Joseph B. (2014-03-01). "Classification of Human Retinal Microaneurysms Using Adaptive Optics Scanning Light Ophthalmoscope Fluorescein Angiography". Investigative Ophthalmology & Visual Science. 55 (3): 1299–1309. doi:10.1167/iovs.13-13122. ISSN 1552-5783. PMC 3943418. PMID 24425852.
^ synd/28 at Who Named It?
^ C. J. Bouchard. Étude sur quelques points de la pathogénie des hémorrhagies cérébrales. Paris, 1867.
^ Gupta, Kashvi; M Das, Joe (2020), "Charcot Bouchard Aneurysm", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 31971704, retrieved 2021-01-01

Cerebrovascular diseases including stroke

Ischaemic stroke

Brain	Anterior cerebral artery syndrome Middle cerebral artery syndrome Posterior cerebral artery syndrome Amaurosis fugax Moyamoya disease Dejerine–Roussy syndrome Watershed stroke Lacunar stroke
Brain stem	Brainstem stroke syndrome Medulla Medial medullary syndrome Lateral medullary syndrome Pons Medial pontine syndrome / Foville's Lateral pontine syndrome / Millard-Gubler Midbrain Weber's syndrome Benedikt syndrome Claude's syndrome
Cerebellum	Cerebellar stroke syndrome
Extracranial arteries	Carotid artery stenosis precerebral Anterior spinal artery syndrome Vertebrobasilar insufficiency Subclavian steal syndrome
Classification	Brain ischemia Cerebral infarction Classification Transient ischemic attack Total anterior circulation infarct Partial anterior circulation infarct
Other	CADASIL Binswanger's disease Transient global amnesia

Haemorrhagic stroke

Extra-axial	Epidural Subdural Subarachnoid
Cerebral/Intra-axial	Intraventricular
Brainstem	Duret haemorrhages
General	Intracranial hemorrhage

Aneurysm

Intracranial aneurysm
- Charcot–Bouchard aneurysm

Other

Categories:

Hidden categories:

Signs and symptoms

Pathophysiology

Diagnosis

History

See also

References