Fibroepithelial neoplasm

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Fibroepithelial neoplasms

Fibroepithelial neoplasm (Phyllodes tumor).
Specialty	Oncology

A fibroepithelial neoplasm (or tumor) is a biphasic tumor. They consist of epithelial tissue, and stromal or mesenchymal tissue. They may be benign or malignant.^[1]

Examples include:

Brenner tumor of the ovary
Fibroadenoma of the breast
Phyllodes tumor of the breast

Sometimes fibroepithelial polyps (FEPs) of the vulva may be misdiagnosed as cancers. However not much harm is caused because the treatment of both is excision. The consent for removal must however be completely informed.^[2]

References

^ Tavassoli, F.A., Devilee, P. (Eds). 2003. World Health Organization Classification of Tumours: Pathology & Genetics: Tumours of the breast and female genital organs. IARC Press: Lyon. ISBN 92-832-2412-4
^ Tripathi PU, Suryarao P, Patvekar MM, Kolte D (June 8, 2024). "Unveiling the Truth: Fibroepithelial Polyp of the Vulva and Its Misdiagnosis as Cancer". Cureus. 16 (6): e61942–e61942. doi:10.7759/cureus.61942. PMC 11229388. PMID 38978881.

External links

derm/346 at eMedicine - "Premalignant Fibroepithelial Tumor"

Glandular and epithelial cancer

Epithelium

Papilloma/carcinoma	Small-cell carcinoma Combined small-cell lung carcinoma Verrucous carcinoma Squamous-cell carcinoma Basal-cell carcinoma Transitional cell carcinoma Inverted papilloma
Complex epithelial	Warthin's tumor Thymoma Bartholin gland carcinoma

Glands

Adenomas/
adenocarcinomas

Gastrointestinal	tract: Linitis plastica Familial adenomatous polyposis pancreas Insulinoma Glucagonoma Gastrinoma VIPoma Somatostatinoma Cholangiocarcinoma Klatskin tumor Hepatocellular adenoma/Hepatocellular carcinoma
Urogenital	Renal cell carcinoma Endometrioid tumor Renal oncocytoma
Endocrine	Prolactinoma Multiple endocrine neoplasia Adrenocortical adenoma/Adrenocortical carcinoma Hürthle cell
Other/multiple	Neuroendocrine tumor Carcinoid Adenoid cystic carcinoma Oncocytoma Clear-cell adenocarcinoma Apudoma Cylindroma Papillary hidradenoma

Adnexal and
skin appendage

sweat gland
- Hidrocystoma
- Syringoma
Syringocystadenoma papilliferum

Cystic,
mucinous,
and serous

Cystic general	Cystadenoma/Cystadenocarcinoma
Mucinous	Signet ring cell carcinoma Krukenberg tumor Mucinous cystadenoma / Mucinous cystadenocarcinoma Pseudomyxoma peritonei Mucoepidermoid carcinoma
Serous	Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma

Ductal,
lobular,
and medullary

Ductal carcinoma	Mammary ductal carcinoma Pancreatic ductal carcinoma Comedocarcinoma Paget's disease of the breast / Extramammary Paget's disease
Lobular carcinoma	Lobular carcinoma in situ Invasive lobular carcinoma
Medullary carcinoma	Medullary breast carcinoma Medullary thyroid cancer

Acinar cell

Acinic cell carcinoma

Connective/soft tissue tumors and sarcomas

Not otherwise specified

Connective tissue neoplasm

Fibromatous

Fibroma/fibrosarcoma	Dermatofibrosarcoma protuberans Desmoplastic fibroma
Fibroma/fibromatosis	Aggressive fibromatosis Aggressive infantile fibromatosis Aponeurotic fibroma Collagenous fibroma Diffuse infantile fibromatosis Familial myxovascular fibromas Fibroma of tendon sheath Fibromatosis colli Infantile digital fibromatosis Juvenile hyaline fibromatosis Plantar fibromatosis Pleomorphic fibroma Oral submucous fibrosis Pachydermodactyly
Histiocytoma/histiocytic sarcoma	Benign fibrous histiocytoma Malignant fibrous histiocytoma Atypical fibroxanthoma Solitary fibrous tumor

Synovial-like

General	Myoma/myosarcoma
Smooth muscle	Leiomyoma/leiomyosarcoma
Skeletal muscle	Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma Sarcoma botryoides Alveolar rhabdomyosarcoma
Leiomyoma Cutaneous Angioleiomyoma Angiolipoleiomyoma Genital leiomyoma Leiomyosarcoma Multiple cutaneous and uterine leiomyomatosis syndrome Multiple cutaneous leiomyoma Neural fibrolipoma Solitary cutaneous leiomyoma STUMP

Complex mixed and stromal

Mesothelial

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