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  1. World Encyclopedia
  2. Infectivity - Wikipedia
Infectivity - Wikipedia
From Wikipedia, the free encyclopedia
Pathogen's ability to infect hosts
Not to be confused with Injectivity.

In epidemiology, infectivity is the ability of a pathogen to establish an infection. More specifically, infectivity is the extent to which the pathogen can enter, survive, and multiply in a host. It is measured by the ratio of the number of people who become infected to the total number exposed to the pathogen.[1]

Infectivity has been shown to positively correlate with virulence, in plants. This means that as a pathogen's ability to infect a greater number of hosts increases, so does the level of harm it brings to the host.[2]

A pathogen's infectivity is different from its transmissibility, which refers to a pathogen's capacity to pass from one organism to another.[1]

See also

[edit]
  • Basic reproduction number (basic reproductive rate, basic reproductive ratio, R0, or r nought)

References

[edit]
  1. ^ a b Oxford textbook of global public health (6th ed.). Oxford: Oxford university press. 2015. p. 1486. ISBN 978-0-19-966175-6.
  2. ^ Stewart, AD; Logsdon, JM; Kelley, SE (April 2005). "An empirical study of the evolution of virulence under both horizontal and vertical transmission". Evolution. 59 (4): 730–739. doi:10.1554/03-330. PMID 15926685. S2CID 924610.
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Clinical research and experimental design
Overview
  • Clinical trial
    • Trial protocols
    • Adaptive clinical trial
  • Academic clinical trials
  • Clinical study design
  • Evidence-based medicine
  • Real world evidence
  • Patient and public involvement
Controlled study
(EBM I to II-1)
  • Randomized controlled trial
    • Scientific experiment
    • Blind experiment
    • Open-label trial
  • Adaptive clinical trial
    • Platform trial
Observational study
(EBM II-2 to II-3)
  • Cross-sectional study vs. Longitudinal study, Ecological study
  • Cohort study
    • Retrospective
    • Prospective
  • Case–control study (Nested case–control study)
  • Case series
  • Case study
  • Case report
Measures
Occurrence
Incidence, Cumulative incidence, Prevalence, Point prevalence, Period prevalence
Association
Risk difference, Number needed to treat, Number needed to harm, Risk ratio, Relative risk reduction, Odds ratio, Hazard ratio
Population impact
Attributable fraction among the exposed, Attributable fraction for the population, Preventable fraction among the unexposed, Preventable fraction for the population
Other
Clinical endpoint, Virulence, Infectivity, Mortality rate, Morbidity, Case fatality rate, Specificity and sensitivity, Likelihood-ratios, Pre- and post-test probability
Trial/test types
  • In vitro
  • In vivo
  • Animal testing
  • Animal testing on non-human primates
  • First-in-man study
  • Multicenter trial
  • Seeding trial
  • Vaccine trial
Analysis of clinical trials
  • Risk–benefit ratio
  • Systematic review
  • Replication
  • Meta-analysis
  • Intention-to-treat analysis
Interpretation of results
  • Selection bias
  • Survivorship bias
  • Correlation does not imply causation
  • Null result
  • Sex as a biological variable
  • Category
  • Glossary
  • List of topics
Authority control databases Edit this at Wikidata
  • GND


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