This is a list of notable people from Niagara Falls, New York.

• George Barker, photographer nationally famous for Niagara Falls photos
• Ruth Dicker, landscape painter
• Jeremiah Goodman, illustrator
• Shelley Niro, Mohawk filmmaker and visual artist
• Alice Wadowski-Bak, artist, creator of wycinanki

• Barbara Frum, Canadian television journalist, born in Niagara Falls, NY
• Lilian Whiting, journalist, author
• Jane Bryant Quinn, financial journalist

• Gary Baker, Grammy Award-winning songwriter
• Glen Benton, death metal musician
• Robert Nathaniel Dett, composer
• Richard Ray Farrell, electric blues guitarist, harmonicist, singer and songwriter, born in Niagara Falls^[1]
• William Masselos, classical pianist
• Chauncey Morehouse, jazz drummer
• Bobby Previte, drummer and composer
• Tommy Tedesco, born in Niagara Falls, most-recorded guitarist in history

• Francis R. Delano, banker, first warden of Minnesota State Prison, first General Superintendent of St. Paul & Pacific Railway
• Frank A. Dudley, former lawyer, politician, hotelier and business owner
• Dawne Hickton, CEO of RTI International Metals

• R. J. Adams (Bob Shannon), actor and radio personality, attended Bishop Duffy High School
• Mark Bridges, costume designer
• Charles Cyphers, actor
• Julie Gregg, actress
• Rachael Lillis, voice actress
• April Stevens, pop singer, best known for her recording of Deep Purple with her brother Nino Tempo
• Nino Tempo, pop singer, best known for his recording of Deep Purple with his sister April Stevens
• Franchot Tone, actor, born in Niagara Falls

• John P. Bobo, received Medal of Honor
• Peter Buell Porter, US Secretary of War

• Earl Brydges, New York State Senator
• John T. Bush, New York State Senator
• John Ceretto, New York State Assemblyman
• Robert H. Gittins, U.S. Congressman
• George W. Grider, U.S. Congressman from Tennessee
• Lorraine Hunt, Lt. Governor of Nevada
• Pat E. Johnson, president of National Tang Soo Do Congress
• Nancy J. King, Maryland State Senator
• Joe Micon, Indiana legislator
• John Moses, Illinois Assemblyman
• Michael Mulligan, lead prosecutor in the courts-martial of Hasan Akbar and of Nidal Malik Hasan
• Peter A. Porter, poet and village president of Niagara Falls
• Arthur Schoellkopf, mayor of Niagara Falls, New York
• James S. Simmons, U.S. Congressman
• Richard D. Simons, Chief Judge of New York Court of Appeals
• Thomas Vincent Welch, New York State Assemblyman, first Superintendent of New York State Reservation at Niagara

• George W. Comstock, public health physician
• Brent Nicholson Earle, AIDS activist
• Robert Elderfield, chemist
• Scott H. Faulring, historian, document editor
• Lois Gibbs, environmental activist
• Orange Judd, agricultural chemist
• James Thomas Stevens, poet, academic

• Benny Bengough, Baseball player and member of the New York Yankees first World Series title in 1923.
• Dean Biasucci, NFL placekicker
• David Bright, professional diver
• Walter Cazen, baseball player
• Adam Clendening, NHL defenseman (raised in nearby Wheatfield)
• Greg Cox, NFL safety
• Modie Cox, basketball player
• Walter Dick, member of U.S. National Soccer Hall of Fame
• Dan DeSantis, football player for Philadelphia Eagles
• Rashad Evans, MMA Fighter
• Jonny Flynn, NBA basketball player, Minnesota Timberwolves
• William Frazer, Olympic sport shooter
• Hank Gornicki, MLB player
• Steve Hamilton, NFL defensive end
• Paul Harris, basketball player
• Ben Hayes, MLB relief pitcher
• Ellis Hobbs, cornerback for Philadelphia Eagles
• Richard Jacob, basketball coach
• Daryl Johnston, NFL player
• Wayne Krivsky, MLB executive
• Chuck Leo, AFL player
• Marc Magliarditi, hockey goaltender
• Sal Maglie, baseball pitcher^[2]
• Rick Manning, baseball player
• Tony Marino, amateur competitive bodybuilder and power lifter
• Matt Mazza, basketball player
• Vince Mazza, NFL player and Canadian football all-star
• Marc Mero, WWE professional wrestler
• John Moir, professional basketball player
• Hank Nichols, college basketball referee
• Qadree Ollison, NFL running back
• Johnny Pasek, baseball player
• Nick Sebek, NFL quarterback
• James Starks, football player for Green Bay Packers
• Tara VanDerveer, women's basketball coach at Stanford
• Kerry Von Erich, professional wrestler
• Jesse Winker, baseball player
• Tim Winn, basketball player

• Vincent DePaul Lynch, university professor
• Peter Magaddino, mobster
• Stefano Magaddino, mafia boss
• William Chandler Shrubsall, inmate
• Charlie Utter, American Wild West figure
• Tobias Witmer, Pennsylvania German dialect poet, surveyor, and American Civil War veteran
• Roger Woodward, went over Niagara Falls and lived in 1960 when he was 7 years old