The following is a list of notable people who were either born/raised or have lived for a significant period of time in the city of Port Harcourt, Rivers State, Nigeria.

• George Abbey (born 1978), footballer
• Precious Achiuwa, basketball player
• Echendu Adiele (1978–2011), footballer
• Friday Ahunanya (born 1971), boxer
• Claude Ake (1939–1996), political scientist
• Mercy Akide (born 1975), former footballer
• Diezani Alison-Madueke (born 1960), former minister of Petroleum Resources^[1]
• Mactabene Amachree (born 1978), basketball player
• Chibuike Amaechi (born 1965), former governor of Rivers State^[2]
• Thankgod Amaefule (born 1984), footballer
• Mark Angel (born 1991), comedian, script writer and motivational speaker
• Napoleon Ashley-Lassen (born 1934), Chief of the Defence Staff of the Ghana Armed Forces
• Izu Azuka (born 1989), footballer

• A. Igoni Barrett (born 1979), writer
• Andre Blaze (born 1983), rapper, reality talent show host
• Nimi Briggs (born 1944), Vice-Chancellor of the University of Port Harcourt
• Burna Boy (born 1991), singer, songwriter

• Monalisa Chinda, actress
• Mercy Chinwo, singer, actress
• Chinonye Chukwu, writer, director
• Tonye Cole (born 1967), businessman

• Agbani Darego (born 1982), model; first Black African Miss World
• George Datoru (born 1978), footballer
• Tonto Dikeh, actress and singer^[3]
• Duncan Dokiwari (born 1973), boxer
• Eddy Lord Dombraye (born 1979), footballer

• Ngozi Ebere (born 1991), footballer
• Emmanuel Ebiede (born 1978), footballer
• Ehie Ogerenye Edison (born 1984), Nigerian politician
• Obinna Ekezie (born 1975), basketball player
• Emmanuella (born 2010), comedian
• Tamara Eteimo (born 1987), actress and singer
• Dino Eze (born 1984), footballer
• Sandra Ezekwesili (born 1989), radio personality

• Ibinabo Fiberesima (born 1973), actress
• Samuel Francis (born 1987), athlete

• Muma Gee (born 1978), singer and actress^[4]
• Finidi George (born 1971), retired footballer
• Odeni George (born 1995), footballer
• Bikiya Graham-Douglas (born 1983), actress and businesswoman

• Christian Ibeagha (born 1990), footballer
• John Ibeh (born 1986), footballer
• Tonye Ibiama (born 1974), businessman
• Bernie Ibini-Isei (born 1992), footballer
• David Ibiyeomie (born 1962), preacher
• Faith Ikidi (born 1987), footballer
• Manasseh Ishiaku (born 1983), footballer

• Nasigba John-Jumbo (born 1988), footballer
• Patience Jonathan (born 1957), former First Lady of Nigeria^[5]

• Ignatius Kattey (born 1948), archbishop

• Obafemi Lasode (born 1955), actor
• Omah Lay, musician

• M-Trill (born 1979), rapper
• Davis Mac-Iyalla (born 1972), LGBT activist
• Chiamaka Madu (born 1996), footballer
• Prince Eze Madumere (born 1964), former Deputy Governor, Imo State
• Maud Meyer, jazz singer
• Duncan Mighty (born 1983), singer, record producer
• Oliver Mobisson (1943–2010), activist
• Mr 2kay, singer^[6]
• Mr Eazi, singer
• Muna, hip hop artist and pageant winner^[7]
• Burna Boy, singer and record producer

• Martin Newland (born 1961), journalist and executive director
• Ajuri Ngelale, Senior Special Assistant to President Muhammadu Buhari on public affairs
• Peter Nieketien (born 1968), former footballer
• Chimaroke Nnamani (born 1960), politician
• Ike Nwachukwu (born 1940), politician
• Chidi Nwanu (born 1967), footballer
• David Nwolokor (born 1996), footballer
• Benji Nzeakor (born 1964), retired footballer
• Priscilla Nzimiro (1923–1951), physician

• Saint Obi, actor
• Chidi Odiah (born 1983), footballer
• Mary Odili (born 1952), Associate Justice of the Supreme Court of Nigeria
• Peter Odili (born 1948), Governor of Rivers State
• Walter Ofonagoro (born 1940), scholar, businessman
• Great Ogboru, businessman and politician
• Timothy Ogene, writer
• David Ojabo (born 2000), American football player
• Chinelo Okparanta, writer
• Aaron Samuel Olanare (born 1994), footballer
• Elkanah Onyeali, footballer
• Daniel Onyekachi (born 1985), footballer
• Yvonne Orji (born 1983), actress
• Richard Daddy Owubokiri (born 1961), retired footballer
• Ukel Oyaghiri (born 1964), lawyer, politician

• Prince Tonye Princewill (born 1969), businessman and politician

• Emmanuella Samuel, YouTube child comedian, best known for appearing in MarkAngelComedy videos
• Zina Saro-Wiwa, video artist and filmmaker
• Jesse Sekidika (born 1996), footballer
• Uchechi Sunday (born 1994), footballer
• Sabinus

• Marco Tagbajumi (born 1988), footballer
• Cleopatra Tawo, radio personality
• Elsie Nwanwuri Thompson, lawyer
• Timaya (born 1977), singer^[8]
• Nwankwo Tochukwu (born 1986), footballer
• Hector Tubonemi (born 1988), footballer

• Colin Udoh, journalist and sports television presenter
• Mary Uranta, actress and businesswoman^[9]

• Waconzy, singer, songwriter
• Adewale Wahab (born 1984), footballer
• Taribo West (born 1974), footballer
• Kay Williamson (1935–2005), linguist

• Albert Yobo (born 1979), footballer
• Joseph Yobo (born 1980), footballer

• List of people from Rivers State