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MCI Screen
Purpose	check mild cognitive impairment

The MCI Screen is a brief neuropsychological test checking for mild cognitive impairment (MCI).

The protocol consists of an immediate recall task, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using correspondence analysis and statistical methods for differentiating normal cognitive function from Mild cognitive impairment. The methodology for scoring the MCI Screen was developed by the Embic Corporation (formerly Medical Care Corporation), a privately held California Corporation.

It was derived from the protocol of the CERAD 10-word recall test.

Validation

The MCI Screen was validated in a study on 471 community dwelling adults whose scores on the Clinical Dementia Rating Scale ranged from 0 (normal: N=119), 0.5 (mild cognitive impairment: N=95), to 1 (mild dementia: N=257). According to a 2005 publication in The Proceedings of the National Academy of Sciences, the MCI Screen has overall accuracy of 98% with sensitivity of 97% for mild cognitive impairment or mild dementia, and 88% specificity for normal aging.^[1] Clinical studies in the USA have shown that the MCI Screen detects early-stage, memory loss due to multiple underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others.^[2] Japan based studies have demonstrated cross-cultural validity of the MCI Screen in clinical and academic settings with accuracy levels equal to those in the USA.^[3]^[4]

References

^ Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24.
^ Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335.
^ Ai Cho, Mika Sugimura, Seigo Nakano, Tatsuo Yamada. Early Detection and Diagnosis of Demented Disorders Using the MCI Screen and Neuroimaging; The Japanese Journal of Clinical and Experimental Medicine. 2007; 84(8):1152-1160.
^ Ai Cho; Mika Sugimura; Seigo Nakano, Tatsuo Yamada. The Japanese MCI Screen for Early Detection of Alzheimer’s Disease and Related Disorders. The American Journal of Alzheimer’s Disease and Other Dementias. 2008; June/July (in press).

v t e Neuropsychological tests
Battery	Cognistat Halstead-Reitan Neuropsychological Battery Luria–Nebraska Neuropsychological Battery Montreal Cognitive Assessment Repeatable Battery for the Assessment of Neuropsychological Status
Arousal/Attention	Continuous performance task D2 Test of Attention Four boxes test Galveston Orientation and Amnesia Test Morningness–eveningness questionnaire Paced Auditory Serial Addition Test Posner cueing task Test of everyday attention Test of Variables of Attention
Sensation/Perception	Bender-Gestalt Test Benton Visual Retention Test Dot cancellation test Judgment of Line Orientation Navon figure Rey–Osterrieth complex figure
Memory	1-2-AX working memory task California Verbal Learning Test Corsi block-tapping test Digit symbol substitution test Doors and People MCI Screen Wechsler Memory Scale
Language	Boston Diagnostic Aphasia Examination Boston Naming Test Comprehensive aphasia test Controlled Oral Word Association Test Thurstone Word Fluency Test
Motor	Compensatory tracking task Purdue Pegboard Test
Problem-solving	Delis–Kaplan Executive Function System Hayling and Brixton tests Tower of London test Trail Making Test Wisconsin Card Sorting Test
Sleep	Epworth Sleepiness Scale
Specific impairments	British Columbia Postconcussion Symptom Inventory Clinical Dementia Rating Digit Cancellation Test Disability Rating Scale Florida Cognitive Activities Scale Glasgow Coma Scale Glasgow Outcome Scale Pediatric Attention Disorders Diagnostic Screener Rivermead post-concussion symptoms questionnaire
Intelligence	National Adult Reading Test Wechsler Adult Intelligence Scale Wechsler Intelligence Scale for Children Wechsler Preschool and Primary Scale of Intelligence Wechsler Test of Adult Reading Raven's Progressive Matrices
Bed-side	Abbreviated mental test score Addenbrooke's Cognitive Examination General Practitioner Assessment of Cognition Mini–mental state examination
Social	Vineland Adaptive Behavior Scale
Malingering	Test of Memory Malingering

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