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Pamlab - Wikipedia

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Alfasigma USA, Inc. (formerly Pamlab) is an American medical food company, and a division of Alfasigma Group, of Bologna, Italy.

Alfasigma's base of operations is located in Bedminster, New Jersey.

History

The company entered the pharmaceutical industry in 1957, initially introducing prescription cough/cold products. In 1987, Pamlab was purchased by Samuel and Judith Camp.^[1]

In early 2013, Pamlab was purchased by Nestlé Health Science.^[2]

In December 2016, Pamlab was purchased by Alfasigma Group of Bologna, Italy.^[3]

Legal actions

Alfasigma USA, Inc. was sued by ExeGi Pharma LLC and the Italian inventor of probiotic VSL#3, Claudio De Simone, for making false advertising claims and ownership rights to VSL#3.^[4]^[5]^[6]

According to court documents: "Defendant VSL Inc., and its licensees Alfasigma and Leadiant, having lost the right to sell the De Simone Formulation, decided to manufacture, market, and sell a different, inferior formulation (the “Fraudulent Formulation”) without conducting any tests to determine if the Fraudulent Formulation would be efficacious in any way".^[6]

A scientific article published in Frontiers in Immunology concluded: "These discrepancies may have a major impact on patient safety and on the liability of doctors when they prescribe a probiotic formulation made with different processes at different production sites from the formulation, which generated the original evidence, without properly informing the patients".^[7]

A class action related to the VSL#3 scandal was recently opened in the USA.^[8]

Products

Alfasigma USA, Inc. produces medical foods for people with diabetic peripheral neuropathy, early memory loss/Alzheimer's, high-risk pregnancy, depression, and other medical conditions.^{[citation needed]}

Some of Alfasigma USA's products include the following:

VSL#3
Deplin
Metanx
Cerefolin
Cerefolin NAC
Neevo DHA
Proxeed Plus
Colief
Carnitine Bulk Ingredients

References

^ "Our History". Pamlab. Retrieved 2016-03-24.
^ "Nestle buys U.S. medical foods firm Pamlab". Reuters. 26 February 2013. Retrieved 2016-03-24.
^ "Alfasigma Expands Footprint" (PDF). 13 January 2017. Archived from the original (PDF) on 22 December 2018. Retrieved 18 July 2017.
^ Simone, C. De (2018). "Letter: what gastroenterologists should know about VSL#3". Alimentary Pharmacology & Therapeutics. 47 (5): 698–699. doi:10.1111/apt.14515. ISSN 1365-2036. PMID 29417631.
^ "De Simone v. VSL Pharmaceuticals, Inc. et al, No. 8:2015cv01356 - Document 927 (D. Md. 2019)". Justia Law. Retrieved 2019-09-01.
^ ^a ^b "Class Action" (PDF).
^ Trinchieri, Vito; Laghi, Luca; Vitali, Beatrice; Parolin, Carola; Giusti, Ilaria; Capobianco, Daniela; Mastromarino, Paola; De Simone, Claudio (2017-11-06). "Efficacy and Safety of a Multistrain Probiotic Formulation Depends from Manufacturing". Frontiers in Immunology. 8: 1474. doi:10.3389/fimmu.2017.01474. ISSN 1664-3224. PMC 5681494. PMID 29163538.
^ "Class Action Accuses Pharma Companies of Secretly Reformulating VSL#3 Probiotics Product". www.classaction.org. 26 July 2019. Retrieved 2019-09-01.

External links

Official website
Alfasigma USA Human Resources Archived 2015-05-04 at the Wayback Machine

Nestlé

Divisions

Nestlé Purina PetCare Nestlé Waters Nestlé Wyeth Nutrition
Divested	BlueTriton Brands (Nestlé Waters North America)

Subsidiaries

Joint ventures

Other assets

Brands

Appliances	BabyNes Dolce Gusto Nespresso Special.T SICAL
Baby nutrition	BabyNes Bear Brand Cerelac Gerber Nido
Baking	Libby's Toll House cookies
Bottled water	Contrex Acqua Panna Perrier Princes Gate Pure Life S.Pellegrino Vittel
Cereals	Cheerios¹ Chocapic Cinnamon Toast Crunch Cookie Crisp¹ Corn Flakes Fitness Golden Grahams¹ Golden Nuggets Lion Cereal Lucky Charms¹ Milo Cereal Nesquik (cereal)^6,7 Trix¹ Shreddies⁷ Shredded Wheat⁷
Chocolate and desserts	Animal Bar Abuelita Aero Aero Biscuits After Eight Allen's Bar One Bertie Beetle Big Turk Blue Riband Black Magic Bono Breakaway Cailler Caramac Carlos V Cheekies Chokito Coffee Crisp Crisp Crunch¹² Drifter Fox's Garoto Goobers Kit Kat³ Kit Kats in Japan Kohler Life Savers¹⁴ Lion Mackintosh's Toffee Matchmakers Menier Chocolate Milkybar Milo Mirage Munchies Negresco Nestlé Milk Chocolate Passatempo Peppermint Crisp Perugina Polo Quality Street Red Ripperz Rolo³ Rowntree's Rowntree's Fruit Gums Rowntree's Fruit Pastilles Sin Parar Smarties⁴ Svitoch TEX Walnut Whip White Knight Yorkie Zvečevo
Coffee and beverages	Abuelita Alpine⁸ Acticor BabyNes Blue Bottle Coffee Boost Carnation^8,9 Caro Chameleon Cold-Brew Chuckie Coffee-Mate Dolce Gusto Huesitos Klim La Lechera Menier Milo cocoa Nescafé Nescafé Azera Nescafé Gold Nescau Nesfruta Nespresso Nesquik Nestea Ovaltine⁴ Ricoré Seattle's Best Coffee Starbucks ¹³ Supligen Sweet Leaf Zoégas
Dairy products	Alpine⁸ Bear Brand^10,11 Carnation^8,9 Coffee-Mate La Lechera Nesquik
Ice cream	D'Onofrio Drumstick¹⁵ Eskimo Pie¹⁵ Fab Frosty Paws¹⁵ Häagen-Dazs^2,15 Hjem-IS Ice Screamers Kit Kat¹⁵ Maxibon Mövenpick Parlour Savory Smarties
Prepared and packaged food and snacks	Buitoni California Pizza Kitchen DiGiorno Herta Hot Pockets Lean Cuisine Libby's Lean Pockets Maggi Stouffer's Thomy Tombstone Uncle Tobys Winiary Wagner Yinlu Foods
Purina PetCare	Alpo Bakers Complete Beggin' Strips Beneful Bonio Dog Chow Fancy Feast Felix Friskies Frosty Paws ONE Winalot
Uncle Tobys	Cheerios¹ PLUS Weeties
Former brands and subsidiaries	Alcon Alfasigma Arrowhead Butterfinger Baby Ruth Chocolate Surpresa Deer Park Dreyer's¹⁵ Enviga Gale's Galderma Laboratories Cetaphil Epiduo Restylane Hoadley's Ice Mountain Jenny Craig Ozarka Peter's Chocolate Poland Spring Polly Waffle PowerBar Powwow Water Rowntree Mackintosh Violet Crumble Wonder Ball Zephyrhills

People

¹ Currently manufactured by General Mills in the U.S. and Canada. Produced by Cereal Partners under the Nestlé brand elsewhere. ² Brand owned by General Mills; U.S. and Canadian production rights controlled by Nestlé under license. ³ U.S. production rights owned by The Hershey Company. ⁴ U.S. rights and production owned by the Smarties Candy Company with a different product. ⁵ U.S. rights and specific trade dress owned by Nestlé; rights elsewhere owned by Associated British Foods. ⁶ Produced by Cereal Partners, branded as Nestlé. ⁷ Produced by Cereal Partners and branded as Nestlé in the U.K. and Ireland. Produced by Post Foods elsewhere. ⁸ Philippine production rights owned by Alaska Milk Corporation. ⁹ Singaporean, Malaysian and Thai production rights owned by Fraser and Neave. ¹⁰ Used only in Indonesia, Thailand, and Cambodia. ¹¹ Used only in the Philippines. ¹² U.S. production rights owned by the Ferrara Candy Company. ¹³ NA rights and specific trade dress to all packaged coffee and other products under the Starbucks brand owned by Nestlé since 2019. ¹⁴ Brand owned by Mars, sold by Nestlé in Canada. ¹⁵ Produced by Froneri in the U.S. since 2020.