From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
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Clinical data | |
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ATC code |
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Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C15H21NO2 |
Molar mass | 247.338 g·mol−1 |
3D model (JSmol) | |
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(verify) |
Prodilidine is an opioid analgesic which is a ring-contracted analogue of prodine. It has around the same analgesic efficacy as codeine, but is only around 1/3 the potency (100mg prodilidine is equivalent to 3mg oral morphine). It has little abuse potential.[1][2][3][4][5]
See also
[edit]References
[edit]- ^ Fraser HF (January 1964). "Addictiveness of 1,2-dimethyl,3-phenyl,3-propionoxy pyrrolidine hydrochloride (ARC I-O-1)". UNODC Bulletin on Narcotics. 16 (1): 37–43.
- ^ Splitter SR (November 1961). "Treatment of pain in patients with a new nonnarcotic analgesic, prodilidine hydrochloride (Cogesic)". Current Therapeutic Research, Clinical and Experimental. 3: 472–7. PMID 13915874.
- ^ Kissel JW, Albert JR, Boxill GC (December 1961). "The pharmacology of prodilidine hydrochloride, a new analgetic agent". The Journal of Pharmacology and Experimental Therapeutics. 134: 332–40. PMID 14456453.
- ^ Weikel JH, Labudde JA (December 1962). "Absorption, excretion and fate of prodilidine". The Journal of Pharmacology and Experimental Therapeutics. 138: 392–8. PMID 13999550.
- ^ Batterman RC, Mouratoff GJ, Kaufman JE (January 1964). "Prodilidine Hydrochloride: A new moderately potent analgesic". The American Journal of the Medical Sciences. 247: 62–8. doi:10.1097/00000441-196401000-00009. PMID 14106881. S2CID 41209143.
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