South Carolina Highway 41
Route information
Maintained by SCDOT
Length	121.5 mi[1] (195.5 km)
Existed	1937–present
Major junctions
South end	US 17 in Mount Pleasant
Major intersections	US 17 Alt. in Jamestown US 521 near Andrews US 378 / SC 51 in Kingsburg US 501 in Ariel Crossroad US 76 / SC 917 in Mullins SC 9 in Lake View
North end	NC 41 at North Carolina state line
Location
Country	United States
State	South Carolina
Counties	Charleston, Berkeley, Georgetown, Williamsburg, Florence, Marion, Dillon
Highway system
South Carolina State Highway System Interstate US State Scenic
← SC 39 → SC 45

South Carolina Highway 41 (SC 41) is a 121.5-mile (195.5 km) state highway, connecting the Charleston region with eastern portions of the Pee Dee region in South Carolina. It serves as an alternative route to U.S. Route 52.

The route travels generally in a south–north direction, beginning in Mount Pleasant and ending at the North Carolina state line just north of Lake View, where it continues as North Carolina Highway 41 towards Lumberton. The route is mostly rural, though it serves as an important arterial in suburban Mount Pleasant and passes through several small towns on its route northwards. It also provides several key river and swamp crossings in the Pee Dee region.

The current SC 41 was established in 1938 on a path from Lake View northeast to the North Carolina state line, where it replaced the original SC 94. The next year, a separate portion of the highway was established from the Marion–Dillon county line northward for about 5 miles (8.0 km). In 1940, the two segments were connected, and the highway was extended to what was then US 76 in Marion. Between 1944 and 1947, SC 41 was re-routed slightly within both Fork and Lake View. In 1949, its southern terminus was shifted to the northwest in Marion, to then end at what was then part of US 501 (now is US 501 Bus.). In September 1951, its path was re-routed in Fork to replace SC 57 to Centenary, SC 175 to Hemingway, and SC 511 to Mount Pleasant. Its former path from Centenary to Fork was redesignated as SC 41 Alt.^[2] In 1970, the highway was shifted off of the bypass around Andrews and was routed through the town. Approximately 25 years later, it was put back on the Andrews bypass; its former path was redesignated as SC 41 Bus.

South Carolina Highway 41
Location	Goose Creek–Society Hill, South Carolina
Existed	1922–1928

South Carolina Highway 41 (SC 41) was an original state highway that was established in 1922 from SC 2 (now U.S. Route 78 (US 78)) near Goose Creek, through Moncks Corner, Kingstree, Lake City, Florence, and Darlington, and ended at SC 50 south-southwest of Cheraw. Approximately three years later, its path from St. Stephen to Kingstree was shifted to the west. Between St. Stephen and Pineville, this replaced the original SC 45 corridor. The former path between Gourdin and Lane was redesignated as SC 412, part of SC 44, and abandoned roadway across the Santee River. In 1927, US 17 was designated along SC 41 from Goose Creek to Florence and US 601 from Florence to the Cheraw area. The next year, the state highway was decommissioned. Most of its path is approximately equal today as US 52.

South Carolina Highway 41
Location	New Zion, South Carolina
Existed	c.1935–1938

South Carolina Highway 41 (SC 41) was a state highway that was established in either 1934 or 1935 from U.S. Route 301 (US 301) west-northwest of the community of New Zion east-southeast to the community. In 1938, it was decommissioned and redesignated as SC 94. Its path is known today as Salem Road.

The Wando River Bridge, a through truss swing bridge built in 1939, was replaced by 2020–2021. The new bridge will be four-lane with median (which can be used as a fifth lane during emergencies), and will be a fixed span bridge, tall enough for tall ships to pass. At a planned cost of $42.3 million, construction began in mid-2015.^[3][4][5]

County	Location	mi[1]	km	Destinations	Notes
Charleston	Mount Pleasant	0.0	0.0	US 17 – Mount Pleasant, Charleston, McClellanville, Georgetown
Berkeley	​	5.0	8.0	Wando River
	Huger	17.2	27.7	SC 402 west – Moncks Corner
	Jamestown	32.3	52.0	US 17 Alt. south / SC 45 – Moncks Corner, St. Stephen	South end of US 17 Alt overlap
Williamsburg	​	38.2	61.5	US 17 Alt. north (Saints Delight Road) – Georgetown, Myrtle Beach	North end of US 17 Alt overlap
	​	43.7	70.3	SC 41 Bus. north (Morgan Avenue) – Andrews
	​	45.3	72.9	US 521 south – Georgetown	South end of US 521 overlap
	Andrews	46.5	74.8	US 521 north / US 521 Bus. south (Main Street) – Kingstree, Manning, Andrews	North end of US 521 overlap
	​	47.9	77.1	SC 41 Bus. south (Morgan Avenue) – Andrews
	​	49.7	80.0	SC 527 west (Thurgood Marshall Highway) – Warsaw, Kingstree
	Rhems	59.2	95.3	SC 51 south (Browns Ferry Road) – Georgetown	South end of SC 51 overlap
	​	61.6	99.1	SC 513 north (County Line Road) – Outland, Yauhannah
	Rome Crossroads	62.8	101.1	SC 512 (Henry Road) – Kingstree
	Hemingway	70.3	113.1	SC 261 (Broad Street) – Conway, Stuckey, Kingstree
Florence	Johnsonville	74.9	120.5	SC 341 west (Broadway Street) – Lake City
	Kingsburg	79.4	127.8	US 378 west / SC 51 north (Myrtle Beach Highway) – Lake City, Florence, Sumter	West end of US 378 and north end of SC 51 overlap
Marion	Gresham	83.0	133.6	US 378 east – Conway	East end of US 378 overlap
	​	88.1	141.8	SC 908 south – Brittons Neck, Conway
	Centenary	91.6	147.4	SC 41 Alt. north – Marion
	Ariel Crossroad	96.3	155.0	US 501 – Conway, Myrtle Beach, Marion	Interchange
	Mullins	106.0	170.6	US 76 / SC 917 east (Mclntyre Street) – Nichols, Loris, Marion	East end of SC 917 overlap
	​	110.0	177.0	SC 917 west – Latta	West end of SC 917 overlap
Dillon	Fork	112.3	180.7	SC 41 Alt. south / SC 57 north – Dillon, Marion	To Little Pee Dee State Park
	Lake View	119.4	192.2	SC 9 (Third Avenue) – Nichols, North Myrtle Beach, Dillon
	​	121.5	195.5	NC 41 north – Fairmont	Continuation beyond North Carolina state line
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

South Carolina Highway 41 Business
Location	Andrews, South Carolina
Length	4.660 mi[6] (7.500 km)
Existed	1996–present

Established between 1993 and 1996, it replaced mainline SC 41 through downtown Andrews. This is second business loop through Andrew, following exactly the same route from 1960-63 until 1970.^[7]

County	Location	mi[8]	km	Destinations	Notes
Williamsburg	​	0.000	0.000	SC 41 – Hemingway, Charleston	Southern terminus
Georgetown	​	1.786– 1.900	2.874– 3.058	To US 521 – Georgetown
	Andrews	3.150	5.069	US 521 Bus. (Main Street) – Georgetown, Kingstree
Williamsburg	​	4.660	7.500	SC 41 (County Line Road) – Charleston, Hemingway	Northern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi

This section is missing mileposts for junctions. Please help by adding them.

South Carolina Highway 41 Alternate
Location	Marion, South Carolina
Length	22.904 mi[9][10] (36.860 km)
Existed	1952–present

South Carolina Highway 41 Alternate (SC 41 Alt.) is a 22.904-mile (36.860 km) alternate route that exists west of the SC 41 mainline path. It connects Centenary and Fork, via Marion, while the mainline travels through Mullins in this area.

Established in 1951 or 1952 as a new alternate route of SC 41 through Marion, though it did replace part of SC 175 south of Marion.^[7]

County	Location	mi[9][10]	km	Destinations	Notes
Marion	Centenary	0.000	0.000	SC 41 – Johnsonville, Charleston, Mullins	Southern terminus
	​	8.934	14.378	US 501 Bus. south to US 501 – Conway, Myrtle Beach, Dillon	Southern end of US 501 Bus. concurrency
	​			SC 576 west – Florence	Eastern terminus of SC 576
	Marion			US 76 (Liberty Street) – Mullins, Florence
		12.214	19.657	US 501 Bus. north (Main Street) – Dillon	Northern end of US 501 Bus. conurrency
	​	15.604	25.112	US 501 – Conway, Dillon	Interchange
	Zion			I-73	Proposed interchange[11][12]
Dillon	Smithboro	21.114	33.980	SC 917 – Mullins, Latta, Bennettsville
	Fork	22.904	36.860	SC 41 / SC 57 – Mullins, Lake View, Dillon	Northern terminus; to Little Pee Dee State Park
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus       Unopened

• U.S. roads portal

• Media related to South Carolina Highway 41 at Wikimedia Commons
• Mapmikey's South Carolina Highways Page: SC 41