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- Understanding of the antitumor immunity role of CD4+ T cells has grown substantially since the late 1990s. CD4+ T cells (mature T-helper cells) play an important...28 KB (4,000 words) - 05:33, 6 May 2024
- The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system...54 KB (6,618 words) - 15:58, 30 April 2025
- gene. CD4+ T helper cells are white blood cells that are an essential part of the human immune system. They are often referred to as CD4 cells, T helper...22 KB (2,581 words) - 20:03, 21 June 2024
- T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells can...72 KB (9,237 words) - 17:50, 21 April 2025
- Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system. They are a kind of large granular...75 KB (9,229 words) - 22:21, 14 April 2025
- anti-tumor immunity and reveal that CD4+ T cells induce more durable immune-mediated tumor control than CD8+ T cells. Even though CD4+ T cells are known...10 KB (1,518 words) - 19:31, 16 September 2024
- cytotoxic T cells (CD8-positive) subset, similar populations appear to exist for both the helper T cells (CD4-positive) and the cytotoxic T cells. Primary...32 KB (3,781 words) - 12:49, 26 April 2024
- Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed...35 KB (4,472 words) - 00:20, 13 June 2024
- PD-L1 (redirect from Programmed cell death 1 ligand 1)signals. In turn, clonal expansion of antigen-specific CD8+ T cells and/or CD4+ helper cells is propagated. The binding of PD-L1 to the inhibitory checkpoint...25 KB (3,052 words) - 15:34, 14 September 2024
- Immunotherapy (redirect from Regulatory T cell therapy)"CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells". Journal...56 KB (6,093 words) - 12:41, 30 April 2025
- other cells such as cytokines, interleukins and growth factors. The surface of CAR T cells can bear either of two types of co-receptors, CD4 and CD8. These...90 KB (9,260 words) - 04:08, 2 April 2025
- receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system...39 KB (4,995 words) - 22:41, 14 December 2024
- "Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity". Cell. 177 (3): 556–571. doi:10.1016/j.cell.2019.02.005. PMC 6954108...35 KB (4,122 words) - 17:20, 24 March 2025
- killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer cells. Many of these cells recognize...14 KB (1,648 words) - 09:58, 18 July 2023
- invariant T cells (MAIT cells) make up a subset of T cells in the immune system that display innate, effector-like qualities. In humans, MAIT cells are found...35 KB (3,966 words) - 16:16, 23 March 2024
- induction of antigen specific T cell response. DC-based immunotherapy is safe and can promote antitumor immune responses and prolonged survival of cancer...14 KB (1,614 words) - 18:48, 17 July 2024
- naïve T cells, TSCM cells are found more abundantly in lymph nodes than in the spleen or bone marrow; but in contrast to naïve T cells, TSCM cells are clonally...18 KB (2,199 words) - 22:28, 23 April 2025
- Murine respirovirus (section Neuraminidase (NA) removal of sialic acid from the surface of malignant cells stimulates natural killers cells and cytotoxic T lymphocytes)highly suppressive CD4+ regulatory T (Treg) cells, which can be distinguished from nonsuppressive T cell. Removing the suppressive Treg cells from human blood...297 KB (32,094 words) - 22:36, 17 April 2025
- innate and adaptive immunity. Type II IFN is primarily secreted by CD4+ T helper 1 (Th1) cells, natural killer (NK) cells, and CD8+ cytotoxic T cells. The...56 KB (6,483 words) - 16:47, 27 December 2024
- criterion listed. Also, HIV viruses generally like to infect CD4+ T-cells. Many of these cells reside in the lymph nodes, so the HIV virus can also generally