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The page "Prelamin-A" does not exist. You can create a draft and submit it for review or request that a redirect be created, but consider checking the search results below to see whether the topic is already covered.

Prelamin-A/C
Prelamin-A/C, or lamin A/C is a protein that in humans is encoded by the LMNA gene. Lamin A/C belongs to the lamin family of proteins. In the setting...

24 KB (2,525 words) - 16:26, 5 February 2025
Progeria (section Lamin A)
for a structural protein called prelamin A, which undergoes a series of processing steps before attaining its final form, called lamin A. Prelamin A contains...

60 KB (6,284 words) - 19:00, 15 May 2025
Lamin (section A- and B-types)
generated in a precursor form called prelamin A. Prelamin A and lamin C differ in structure only at the carboxyl-terminus. Here, prelamin A contains two...

18 KB (2,198 words) - 02:12, 10 March 2025
Progerin
A. This mutation activates a cryptic splice site that induces a larger mutation in the processed prelamin A messenger RNA, causing the deletion of a 50...

9 KB (1,036 words) - 15:42, 31 May 2024
Nuclear prelamin A recognition factor
Nuclear prelamin A recognition factor, also known as NARF, is a protein which in humans is encoded by the NARF gene. Several proteins have been found...

6 KB (713 words) - 02:17, 28 March 2024
Restrictive dermopathy
ZMPSTE24, which encodes a protein responsible for the cleavage of farnesylated prelamin A into mature non-farnesylated lamin, or by a mutation in the LMNA...

3 KB (195 words) - 22:59, 24 March 2025
Laminopathy
process prelamin A into mature lamin A, mutations in this gene abolishing protease activity cause defects similar to laminopathies caused by prelamin A with...

33 KB (3,439 words) - 20:33, 16 March 2025
ZMPSTE24 (category Protein pages needing a picture)
lamin A, because the latter is a substrate for the former. In humans, a mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid...

5 KB (588 words) - 20:55, 3 March 2023
Progeroid syndromes (section Defects in Lamin A/C)
In the truncated lamin A precursor, this cleavage is not possible and the prelamin A cannot mature. When the truncated prelamin A is localized to the nuclear...

74 KB (8,748 words) - 15:14, 24 November 2024
Narf
to: Narf, a fictional creature; A sea nymph in the film Lady in the Water Native American Rights Fund, an American law firm Nuclear prelamin A recognition...

538 bytes (102 words) - 19:50, 18 October 2021
Nuclear prelamin A recognition factor like
Nuclear prelamin A recognition factor like is a protein that in humans is encoded by the NARFL gene. GRCh38: Ensembl release 89: ENSG00000103245 – Ensembl...

1 KB (150 words) - 21:01, 22 November 2022
Fluorescence-lifetime imaging microscopy
Buendia, Brigitte (2006). "The truncated prelamin A in Hutchinson–Gilford progeria syndrome alters segregation of A-type and B-type lamin homopolymers" (PDF)...

24 KB (3,092 words) - 21:09, 11 July 2024
Nuclear lamina
maturation of prelamin A show increased DNA damage and chromosome aberrations and are more sensitive to DNA damaging agents. Apoptosis is a form of programmed...

15 KB (1,862 words) - 21:56, 28 November 2024
DNA damage theory of aging
maturation of prelamin A show increased DNA damage and chromosome aberrations and are more sensitive to DNA damaging agents. Cockayne Syndrome is due to a defect...

97 KB (11,163 words) - 08:06, 6 January 2025
Evolution of ageing
and homologous recombination. Mouse cells deficient for maturation of prelamin A show increased DNA damage and chromosome aberrations and have increased...

55 KB (6,801 words) - 18:19, 26 November 2024
ANKRD2
been shown to interact with Titin YBX1, TCAP, PML and TP53. Lamin A and prelamin A Akt. GRCh38: Ensembl release 89: ENSG00000165887 – Ensembl, May 2017...

22 KB (2,824 words) - 17:03, 26 April 2025
FNTB
Sinensky M, Fantle K, Trujillo M, et al. (1994). "The processing pathway of prelamin A". J. Cell Sci. 107 (1): 61–7. doi:10.1242/jcs.107.1.61. PMID 8175923....

7 KB (868 words) - 15:57, 15 January 2024
Stress granule
associated with 40S ribosomal subunits, translation initiation factors, poly(A)+ mRNA and RNA-binding proteins (RBPs). While they are membraneless organelles...

184 KB (12,563 words) - 05:08, 10 March 2025
Disposable soma theory of aging
and homologous recombination. Mouse cells deficient for maturation of prelamin A show increased DNA damage and chromosome aberrations and have increased...

36 KB (4,388 words) - 18:15, 26 November 2024
Karl Tryggvason
Rodríguez, Francisco; Tryggvason, Karl; López-Otín, Carlos (2002). "Defective prelamin a processing and muscular and adipocyte alterations in Zmpste24...

16 KB (1,588 words) - 00:35, 28 March 2025

Word definitions from Wiktionary
prelamin
From pre- +‎ lamin. prelamin (plural prelamins) (biochemistry) Any of a group of precursors of lamins Palmerin
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