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Ven-A-Care of the Florida Keys is one of the most financially successful whistleblowers in the history of the United States.^[1][2] The four-person team^[1] specialized in being relators for qui tam suits in healthcare overbilling, producing more than $2.2B in revenue for the government and $380M for themselves and their legal team.^[3] During a study conducted on whistleblowing efforts between November 2010 and July 2012, they accounted for almost half of the money from whistleblower-prompted federal and state settlements.^[4]

Ven-A-Care is additionally unusual for being what are termed outside relators, or people who investigate companies they have no other formal relationship with in order to find and report wrongdoing.^[1][3] As a consequence of this, they also have filed whistleblower suits against an unusually large number of unique defendants.

Ven-A-Care was co-founded by Mark Jones and Luis Cobo^[3] as a four-person^[1] pharmacy in the 1987.^[5] They specialized in to providing end-of-life care to HIV and cancer patients during the AIDS Crisis. This came primarily in the form of home infusions.^[6]

In 1991 W. R. Grace and Company allegedly approached Ven-A-Care about partnering to open a new AIDS clinic, termed National Medical Care Inc. In lawsuits, Ven-A-Care alleged that National Medical Care Inc intended to choose the drugs that would make the clinic the most money, rather than selecting the drugs for medical reasons.^[6]

The new clinic significantly negatively impacted Ven-A-Care's operations, and eventually lead to their first qui tam lawsuit in 1994.^[6] The ensuing $500M settlement in 2000 against National Medical Care Inc broke Department of Justice records and included a $100M criminal penalty.^[7]

Much of Ven-A-Care's litigation was based on alleged manipulation of the calculation of average wholesale price for Medicare and Medicare billing.^[8]

In 2001, a Ven-A-Care case with Bayer reached a settlement.^[9]

In 2005, a Ven-A-Care case with GlaxoSmithKline Pharmaceuticals settled.^[10]

In 2007, a Ven-A-Care case reached a settlement with Bristol Myers Squibb and its subsidiary Apothecon.^[11] Another case, with Aventis Pharma also settled.^[12][13]

In 2009, Ven-A-Care's cases with four pharmaceutical companies (Mylan, AstraZeneca, Ortho-McNeil Pharmaceutical, and UDL Laboratories) settled over a Medicaid Drug Rebate Program suit.^[14] A case against Schering-Plough also settled that year,^[15][16] as did an additional one with Teva Pharmaceuticals.^[17]

In 2010, they secured settlements against Abbott Laboratories^[3] B. Braun and Roxane Labs,^[18][19] and the Dey family of companies.^[5][20]

In 2011, after 18 cases handled by settlement, a Ven-A-Care secured its first trial victory over Actavis.^[3] The verdict was appealed, and the eventual settlement was for far less.^[21] A separate case against Par Pharmaceutical also settled.^[22][2] Two additional cases against Watson Pharmaceuticals and a unit of Novartis also settled.^[23]

In 2013, Ven-A-Care settled a price manipulation case against Pfizer.^[24]

In 2017, Ven-A-Care settled a second case against Mylan,^[25] this time with former defendant Sanofi (via Avantis) as a co-relator.^[26]