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Technopedia Center
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Faculty of Engineering and Computer Science
S1 Informatics S1 Information Systems S1 Information Technology S1 Computer Engineering S1 Electrical Engineering S1 Civil Engineering

faculty of Economics and Business
S1 Management S1 Accountancy

Faculty of Letters and Educational Sciences
S1 English literature S1 English language education S1 Mathematics education S1 Sports Education
teknopedia

Flag Counter
  2. World Encyclopedia
  3. LP-211 - Wikipedia
LP-211 - Wikipedia
From Wikipedia, the free encyclopedia
LP-211
Identifiers
  • N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC30H34N4O
Molar mass466.629 g·mol−1
3D model (JSmol)
  • N#Cc3ccc(cc3)CNC(=O)CCCCCN(CC2)CCN2c1ccccc1-c4ccccc4
  • InChI=1S/C30H34N4O/c31-23-25-14-16-26(17-15-25)24-32-30(35)13-5-2-8-18-33-19-21-34(22-20-33)29-12-7-6-11-28(29)27-9-3-1-4-10-27/h1,3-4,6-7,9-12,14-17H,2,5,8,13,18-22,24H2,(H,32,35) ☒N
  • Key:BQEDZLDNNBDKDS-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

LP-211 is a drug which acts as a potent and selective agonist at the 5HT7 serotonin receptor, with better brain penetration than older 5-HT7 agonists in the same series, and similar effects in animals.[1][2]

See also

References

  1. ^ Hedlund PB, Leopoldo M, Caccia S, Sarkisyan G, Fracasso C, Martelli G, Lacivita E, Berardi F, Perrone R (August 2010). "LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor". Neuroscience Letters. 481 (1): 12–6. doi:10.1016/j.neulet.2010.06.036. PMC 2910240. PMID 20600619.
  2. ^ Monti JM (August 2011). "Serotonin control of sleep-wake behavior". Sleep Medicine Reviews. 15 (4): 269–81. doi:10.1016/j.smrv.2010.11.003. PMID 21459634.
Sunting pranala
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