SLC2A11

SLC2A11
Identifiers
Aliases	SLC2A11, GLUT10, GLUT11, solute carrier family 2 member 11
External IDs	OMIM: 610367; HomoloGene: 57126; GeneCards: SLC2A11; OMA:SLC2A11 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	23,886,312 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; sural nerve; ; apex of heart; ; pituitary gland; ; body of pancreas; ; nucleus accumbens; ; anterior pituitary; ; left ventricle; ; hypothalamus; ; human kidney;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	transporter activity; transmembrane transporter activity; sugar transmembrane transporter activity;
Cellular component	integral component of membrane; cell junction; plasma membrane; membrane; nucleus;
Biological process	carbohydrate transport; transmembrane transport; hexose transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	66035
	n/a
	ENSG00000275744; ENSG00000133460
	n/a
	Q9BYW1
	n/a
	NM_001024938; NM_001024939; NM_001282864; NM_030807
	n/a
	NP_001020109; NP_001020110; NP_001269793; NP_110434
	n/a
	Wikidata
View/Edit Human

Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11) also known as glucose transporter type 10/11 (GLUT-10/11) is a protein that in humans is encoded by the SLC2A11 gene.^[3]

SLC2A11 belongs to a family of plasma membrane proteins that mediate transport of sugars across the membrane by facilitative diffusion.^[3]^[4]

References

^ ^a ^b ^c ENSG00000133460 GRCh38: Ensembl release 89: ENSG00000275744, ENSG00000133460 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: Solute carrier family 2 (facilitated glucose transporter), member 11".
^ Sasaki T, Minoshima S, Shiohama A, Shintani A, Shimizu A, Asakawa S, Kawasaki K, Shimizu N (December 2001). "Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of transcription variants". Biochemical and Biophysical Research Communications. 289 (5): 1218–24. doi:10.1006/bbrc.2001.6101. PMID 11741323.

Doege H, Bocianski A, Scheepers A, Axer H, Eckel J, Joost HG, Schürmann A (October 2001). "Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle". The Biochemical Journal. 359 (Pt 2): 443–9. doi:10.1042/0264-6021:3590443. PMC 1222165. PMID 11583593.
Wu X, Li W, Sharma V, Godzik A, Freeze HH (May 2002). "Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues". Molecular Genetics and Metabolism. 76 (1): 37–45. doi:10.1016/s1096-7192(02)00018-5. PMID 12175779.
Scheepers A, Schmidt S, Manolescu A, Cheeseman CI, Bell A, Zahn C, Joost HG, Schürmann A (2005). "Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue". Molecular Membrane Biology. 22 (4): 339–51. doi:10.1080/09687860500166143. PMID 16154905. S2CID 40473467.
Manolescu AR, Augustin R, Moley K, Cheeseman C (2007). "A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity". Molecular Membrane Biology. 24 (5–6): 455–63. doi:10.1080/09687680701298143. PMID 17710649. S2CID 35331716.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] ENSG00000133460 GRCh38: Ensembl release 89: ENSG00000275744, ENSG00000133460 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: Solute carrier family 2 (facilitated glucose transporter), member 11".

[pmid11741323-4] Sasaki T, Minoshima S, Shiohama A, Shintani A, Shimizu A, Asakawa S, Kawasaki K, Shimizu N (December 2001). "Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of transcription variants". Biochemical and Biophysical Research Communications. 289 (5): 1218–24. doi:10.1006/bbrc.2001.6101. PMID 11741323.

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Epstein Files Full PDF

References

Further reading