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  1. World Encyclopedia
  2. Cefcapene
Cefcapene
From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Cefcapene
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
  • J01DD17 (WHO)
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • (6R,7R)-3-{[(Aminocarbonyl)oxy]methyl}-7-{(Z)-[2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino}-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
CAS Number
  • 135889-00-8 checkY
PubChem CID
  • 6436055
ChemSpider
  • 4940731 ☒N
UNII
  • 4D5D3422MW
KEGG
  • D07638 checkY
ChEBI
  • CHEBI:131729 ☒N
ChEMBL
  • ChEMBL582912 ☒N
Chemical and physical data
FormulaC17H19N5O6S2
Molar mass453.49 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=C/CC)\c3nc(sc3)N)COC(=O)N)C(=O)O
InChI
  • InChI=1S/C17H19N5O6S2/c1-2-3-8(9-6-30-16(18)20-9)12(23)21-10-13(24)22-11(15(25)26)7(4-28-17(19)27)5-29-14(10)22/h3,6,10,14H,2,4-5H2,1H3,(H2,18,20)(H2,19,27)(H,21,23)(H,25,26)/b8-3-/t10-,14-/m1/s1 ☒N
  • Key:HJJRIJDTIPFROI-NVKITGPLSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Cefcapene (INN) is a third-generation cephalosporin antibiotic.

It was patented in 1985 and approved for medical use in 1997.[1]

References

[edit]
  1. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 496. ISBN 9783527607495.
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Antibacterials active on the cell wall and envelope (J01C-J01D)
β-lactams
(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases
)
Penicillins (Penams)
Narrow
spectrum
β-lactamase sensitive
(1st generation)
  • Benzylpenicillin (G)#
  • Benzathine benzylpenicillin#
  • Procaine benzylpenicillin#
  • Phenoxymethylpenicillin (V)#
  • Propicillin‡
  • Pheneticillin‡
  • Azidocillin‡
  • Clometocillin‡
  • Penamecillin‡
β-lactamase resistant
(2nd generation)
  • Cloxacillin# (Dicloxacillin
  • Flucloxacillin)
  • Oxacillin
  • Nafcillin
  • Methicillin‡
Extended
spectrum
Aminopenicillins (3rd generation)
  • Amoxicillin#
  • Ampicillin# (Pivampicillin
  • Hetacillin‡
  • Bacampicillin‡
  • Lenampicillin
  • Metampicillin‡
  • Talampicillin‡)
  • Epicillin‡
Carboxypenicillins (4th generation)
  • Ticarcillin
  • Carbenicillin‡ / Carindacillin‡
  • Temocillin‡
Ureidopenicillins (4th generation)
  • Piperacillin
  • Azlocillin‡
  • Mezlocillin‡
Other
  • Mecillinam (Pivmecillinam)
  • Sulbenicillin‡
Carbapenems / Penems
  • Carbapenems (Ertapenem
  • Antipseudomonal (Doripenem
  • Imipenem
  • Meropenem)
  • Biapenem‡
  • Panipenem)
  • Penems (Faropenem
  • Ritipenem§
  • Sulopenem)
Cephems
Cephalosporins
Cephamycins
Carbacephems
1st generation
  • Cefazolin#
  • Cefalexin #
  • Cefadroxil
  • Cefapirin
  • Cefazedone‡
  • Cefazaflur‡
  • Cefradine‡
  • Cefroxadine‡
  • Ceftezole‡
  • Cefaloglycin‡
  • Cefacetrile‡
  • Cefalonium‡
  • Cefaloridine‡
  • Cefalotin
  • Cefatrizine‡
2nd generation
  • Cefaclor
  • Cefprozil
  • Cefuroxime
  • Cefuroxime axetil
  • Cefamandole‡
  • Cefonicid‡
  • Ceforanide‡
  • Cefuzonam‡
  • Cephamycin (Cefoxitin
  • Cefotetan
  • Cefminox‡
  • Cefbuperazone‡
  • Cefmetazole‡)
  • Carbacephem (Loracarbef‡)
3rd generation
  • Cefixime#
  • Ceftriaxone#
  • Cefotaxime#
  • Antipseudomonal (Ceftazidime#
  • Cefoperazone)
  • Cefdinir
  • Cefcapene
  • Cefdaloxime
  • Ceftizoxime
  • Cefmenoxime
  • Cefpiramide
  • Cefpodoxime
  • Ceftibuten
  • Cefditoren
  • Cefotiam‡
  • Cefetamet‡
  • Cefodizime‡
  • Cefpimizole‡
  • Cefsulodin‡
  • Cefteram‡
  • Ceftiolene‡
  • Oxacephem (Flomoxef
  • Latamoxef‡)
4th generation
  • Cefepime
  • Cefozopran‡
  • Cefpirome
  • Cefquinome‡
5th generation
  • Ceftaroline fosamil
  • Ceftolozane
  • Ceftobiprole
Siderophore
  • Cefiderocol#
Veterinary
  • Ceftiofur
  • Cefquinome
  • Cefovecin
Monobactams
  • Aztreonam
  • Tigemonam‡
  • Carumonam‡
  • Nocardicin A‡
β-lactamase inhibitors
  • Penam (Sulbactam
  • Tazobactam
  • Enmetazobactam)
  • Clavam (Clavulanic acid)
  • non-β-lactam (Avibactam
  • Durlobactam
  • Relebactam
  • Taniborbactam
  • Vaborbactam)
Combinations
  • Amoxicillin/clavulanic acid#
  • Ampicillin/flucloxacillin
  • Ampicillin/sulbactam (Sultamicillin)
  • Aztreonam/avibactam
  • Benzathine benzylpenicillin/procaine benzylpenicillin
  • Cefepime/enmetazobactam
  • Cefepime/sulbactam
  • Cefoperazone/sulbactam
  • Ceftazidime/avibactam
  • Ceftolozane/tazobactam
  • Imipenem/cilastatin#
  • Imipenem/cilastatin/relebactam
  • Meropenem/vaborbactam
  • Panipenem/betamipron
  • Piperacillin/tazobactam
  • Sulbactam/durlobactam
  • Sulopenem/probenecid
  • Ticarcillin/clavulanic acid
Polypeptides
Lipopeptides
  • Insert into bacterial cell wall causing perforation and depolarization: Daptomycin
  • Surfactin
Other
  • Inhibits PG elongation and crosslinking: Ramoplanin§
Intracellular
  • Inhibit PG subunit synthesis and transport: NAM synthesis inhibition
    • Fosfomycin
  • DADAL/AR inhibitors
    • Cycloserine
    • Terizidone
  • bactoprenol inhibitors
    • Bacitracin
Other
  • Hydrolyze NAM-NAG
    • Lysozyme
  • Tyrothricin
    • Gramicidin
    • Tyrocidine
  • Isoniazid#
  • Teixobactin
  • #WHO-EM
  • ‡Withdrawn from market
  • Clinical trials:
    • †Phase III
    • §Never to phase III
Stub icon

This systemic antibiotic-related article is a stub. You can help Wikipedia by adding missing information.

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Retrieved from "https://en.wikipedia.org/w/index.php?title=Cefcapene&oldid=1330776514"
Categories:
  • Cephalosporin antibiotics
  • Thiazoles
  • Antibiotic stubs
Hidden categories:
  • Articles with short description
  • Short description matches Wikidata
  • Short description is different from Wikidata
  • Drugs with non-standard legal status
  • Articles with changed ChemSpider identifier
  • Articles with changed EBI identifier
  • Articles with changed InChI identifier
  • Chemical pages without DrugBank identifier
  • Drugboxes which contain changes to verified fields
  • Drugboxes which contain changes to watched fields
  • All stub articles

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